The General Application Instructions (GAI) are designed to be read in conjunction with the program announcement for a funding opportunity offered by the Congressionally Directed Medical Research Programs (CDMRP). The program announcement provides basic information necessary to prepare an application (i.e., what to submit), whereas the GAI provides additional details and instruction for both application preparation and submission (i.e., how to submit). For accurate referencing, ensure that the version on the cover page of the GAI matches the version indicated on the front page of the program announcement.

The following symbols are used throughout the GAI:

Marks particularly helpful or important information.

Refers the reader to the program announcement for specific instructions or additional information.

B. Current Funding Opportunities and Email Notifications

Funding opportunities currently offered through the U.S. Army Medical Research and Development Command (USAMRDC), including those issued by the CDMRP, may be viewed at the Grants.gov Search Grants page; users should enter Assistance Listing (AL) Number 12.420 when searching for CDMRP funding opportunities. Applicants should subscribe on Grants.gov to receive official notifications of new funding opportunity postings and updates. Applicants are encouraged to sign up to receive notifications of changes to specific funding opportunities through either: (1) the Subscribe button on the Synopsis page for the specific program announcement; or (2) the Manage Subscriptions option on the Connect pull-down menu.

It is incumbent upon the applicant to check for published updates to the funding opportunity and the application package prior to submission; the applicant is responsible for using the latest version of the full application package. If the Grants.gov application package is updated or changed, then previous versions of the application package may not be accepted by Grants.gov.

Information about funding opportunities is available on the CDMRP Open Funding Opportunities page and on the electronic Biomedical Research Application Portal (eBRAP) Funding Opportunities and Forms page. Applicants can receive email notifications of funding opportunity releases by subscribing on eBRAP. Email notifications of funding opportunities from eBRAP are sent as a courtesy.

To facilitate that email correspondence is delivered correctly, and not treated as spam, Principal Investigators (PIs) and organizational representatives should keep email addresses up to date in both Grants.gov and eBRAP; and place the following domains into any available email �safelists�: health.mil, eBRAP.org and Grants.gov. The same email addresses should be used when submitting both the pre-application and the full application.

C. Agency Contacts

eBRAP Help Desk: Questions related to program announcement content or submission requirements, as well as questions related to submission of pre-applications, or full applications from intramural organizations, through eBRAP, should be directed to the eBRAP Help Desk, which is available Monday through Friday from 8:00 a.m. to 5:00 p.m. Eastern Time (closed on most U.S. federal holidays). Response times may vary depending on the volume of inquiries. The eBRAP Help Desk will not provide Grants.gov submission assistance.

Phone:�� 301-682-5507

Email:�� [email protected]

Grants.gov Support Center: Questions related to application submission through the Grants.gov portal should be directed to the Grants.gov Support Center, which is available 24 hours a day, seven days a week (closed on U.S. federal holidays).

Phone:�� 800-518-4726; International 1-606-545-5035

Email:�� [email protected]

D. Application and Award Information

Timelines: Awards made from CDMRP funding opportunities will be funded with Defense Health Program Research, Development, Test and Evaluation (RDT&E) appropriations. RDT&E funds must be obligated to a specific award or purpose within 24 months from the start of the fiscal year in which the funds were appropriated (e.g., fiscal year 2025 [FY25] funds must be obligated no later than 30 September 2026). In addition to obligation deadlines, RDT&E funds are available for use for a limited time period and close for disbursement five years after the obligation deadline. Closed (i.e., undisbursed) funds are returned to the U.S. Treasury at the end of the five-year disbursement period (e.g., FY25 funds close for disbursement to performers 30 September 2031).

Pre-Award Costs: An institution of higher education, hospital, other nonprofit, or for-profit organization may, at its own risk and without the government�s prior approval, incur obligations and expenditures to cover costs up to 90 days before the beginning date of the initial budget period of a new award if such costs: (1) are necessary to conduct the project; and (2) would be allowable under the award, if awarded. If specific expenditures would otherwise require prior approval, the recipient must obtain the Grants Officer�s approval before incurring the cost. Government prior approval is required for any costs to be incurred more than 90 days before the beginning date of the initial budget period of a new award.

Incurring pre-award costs in anticipation of an award imposes no obligation on the government either to make the award or to increase the amount of the approved budget if an award is made for less than the amount anticipated and is inadequate to cover the pre-award costs incurred or in the absence of appropriations. The government expects the recipient to be fully aware that pre-award costs result in borrowing against future support and that such borrowing must not impair the organization�s ability to accomplish the project objectives within the approved timeframe or in any way adversely affect the conduct of the project.

II. INTRODUCTION TO APPLICATION SUBMISSION

A. Eligible Applicant Organizations

Unless otherwise specified in the program announcement, applications may be submitted by extramural organizations and intramural Department of Defense (DOD) organizations, defined as follows:

Extramural Organization: An eligible foreign or domestic non-DOD organization. Examples of extramural organizations include, but are not limited to, academic institutions, biotechnology companies, foundations, federal government organizations other than the DOD (i.e., intragovernmental organizations), and research institutes.

Intramural DOD Organization: Refers specifically to DOD organizations including DOD laboratories, DOD military treatment facilities, and/or DOD activities embedded within a civilian medical center.

B. Applications Involving Intragovernmental or Intramural DOD Organizations

To provide information specific to intragovernmental and intramural DOD investigators contributing to the submission of an application, the CDMRP developed a Guide for Intragovernmental and Intramural DOD Applicants. Applicants are recommended to reference this guide for additional information and considerations unique to intragovernmental and intramural organizations.

Funding to Intragovernmental and Intramural DOD Organizations: Intragovernmental and intramural DOD organizations must be prepared to accept the entirety of the requested budget for the proposed work in the fiscal year funds indicated in the funding opportunity. Congressional Special Interest (CSI) appropriations for a given program or topic are not part of the requested DOD budget, and there is no guarantee for future funding. Intragovernmental and intramural DOD investigators are responsible for coordinating the use of funding agreements, contractual or otherwise, to support any extramural collaborators as appropriate. Intragovernmental and intramural DOD investigators and collaborators are reminded to

coordinate the receipt and commitment of funds through their respective Resource Manager (RM), Task Area Manager, Comptroller or equivalent Business Official.

The USAMRDC�s RM office will �direct fund� Intragovernmental/Intramural DOD Organizations by utilizing Title 41 United States Code (USC) 6307, the Project Order Statute, or 31 USC 1535, the Economy Act Statute, as appropriate. Provided all criteria are met, the CDMRP will use the Project Order Statute as the preferred transactional authority to fund intramural DOD organizations. The USAMRDC RM will fund by the authorized method through the Military Interdepartmental Purchase Request (MIPR), Funding Authorization Document (FAD), or Direct Charge Work Breakdown Structure processes. Transfer of funds is contingent upon appropriate safety and administrative approvals.

Funding of Extramural Organizations Collaborating with an Intragovernmental or Intramural DOD Organization: Direct transfer of funds from any extramural award recipient to an intragovernmental or intramural DOD organization is not allowed except under very limited circumstances. As noted above, funding of intragovernmental or intramural DOD organizations, including research collaborators, will be managed through a direct funds transfer from the USAMRDC�s RM office.

Cooperative Research and Development Agreement (CRADA): If an extramural collaborator will be involved in the performance of the proposed research with an Intragovernmental or Intramural DOD organization, a CRADA or other instrument (as authorized by law or regulation) with the collaborator may be necessary before work between the organizations can begin. The CRADA (or other instrument) is not required at the time of application submission. A timeline for execution of the CRADA should be included within the project�s Statement of Work (SOW).

C. Pre-Application and Full Application Submission Portal Systems

The eBRAP is a secure web-based system that allows PIs and/or organizational representatives to receive communications from the CDMRP and to submit their pre-applications. Intramural DOD organizations may submit full applications through eBRAP.

Additionally, the eBRAP system allows a submitting organization�s representatives and PIs to view and modify certain components of their full application submission package(s) during a specified verification period. eBRAP validates full application files against the specific program announcement requirements and notes discrepancies in an email to the PI as well as in the Full Application Files tab in eBRAP. During the verification period, it is the applicant�s responsibility to review all application components for accuracy and to ensure proper ordering as specified in the program announcement. All verification periods are specified in the program announcement.

Grants.gov is a federal system that must be used by funding agencies to announce extramural grant applications. Full applications for CDMRP funding opportunities can only be submitted to Grants.gov after submission of a pre-application through eBRAP. Extramural organizations must submit full applications through Grants.gov.

D. Application Submission Overview

Application submission is a two-step process. Successful completion of BOTH steps is required for all applications.

STEP 1. Pre-application submission: All pre-applications for both extramural and intramural organizations must be submitted through eBRAP.

STEP 2. Full application submission: Full applications must be submitted through the online portals as described below.

Grants.gov: Full applications from extramural organizations must be submitted through Grants.gov Workspace. Refer to Section IV, Full Application Submission Through Grants.gov for application preparation and submission instructions.

eBRAP: Only full applications submitted by an intramural DOD organization may be submitted through eBRAP. Refer to Section V, Full Application Submission Through eBRAP for application preparation and submission instructions. Full applications from extramural organizations, including non-DOD federal organizations, received through eBRAP will be withdrawn.

Regardless of submission portal used, all pre-application and application components must be submitted by the deadlines stipulated in the program announcement. Failure to meet any of the deadlines will result in application rejection.

The following information must be identical between the pre-application and the full application for eBRAP to process the submission: application title, PI information; Business Official(s) information, performing organization and contracting organization.

Additionally, the correct eBRAP log number associated with the application must be used throughout the entire submission process. Inconsistencies may delay application processing and limit or negate the ability to view, modify, and verify the application in eBRAP during the application verification period.

If the funding mechanism allows for Partnering PIs, the U.S. Army Medical Research Acquisition Activity (USAMRAA) requires separate full application package submissions for the Initiating PI and each Partnering PI, even if the PIs are located within the same organization. The Partnering PI application is an abbreviated package that only includes components required to make a separate award. Initiating and Partnering PIs will each be assigned a unique eBRAP log number. Each full application package must be submitted using the unique eBRAP log number. All associated applications (the Initiating PI�s and Partnering PI�s) must be submitted by the full application submission deadline.

III. PRE-APPLICATION SUBMISSION

General information about eBRAP registration and pre-application submission is provided in this section. The eBRAP Applicant User Guide contains detailed instructions for these two processes.

A. eBRAP Registration

PIs must register in eBRAP to submit a pre-application.

It is strongly recommended that PIs start the eBRAP registration process early to ensure sufficient time for completion prior to the submission deadline. There is no grace period.

PIs are required to utilize an Open Researcher and Contributor ID (ORCID) identifier and should enter that information in the appropriate field in the My Profile tab in the Account Information section of eBRAP.

During eBRAP registration, the PI must request to be affiliated with their organization from the list of organizations already registered with eBRAP. If the PI�s organization is not already registered with eBRAP, the PI must invite an Authorized Organizational Representative (AOR), also known as a Primary Organization Representative, to register the organization. The AOR does not need to complete the organization registration in eBRAP prior to the pre-application submission deadline in order for the pre-application to be submitted. However, the organization�s eBRAP registration must be completed before the full application submission deadline to allow for processing, viewing, and modifying select components of the full application package during the application verification period.

Extramural Organizations: Applicants should ensure that the names and email addresses used during eBRAP registration are the same as the names and email addresses used on the Application for Federal Assistance Standard Form 424 (Research & Related), SF424 (R&R) Form, submitted through Grants.gov Workspace.

Intramural Organizations: Applicants should ensure that the names and email addresses used during eBRAP registration are the same as the names and email addresses that will be provided when the full application package is submitted through eBRAP.

B. Content and Form of Pre-Application Submission � eBRAP

For specific instructions regarding content of the pre-application submission components, refer to Section 5.3.1, Pre-Application Submission, in the program announcement.

All pre-application components must be submitted through eBRAP by the deadline specified in the program announcement.

To start a new pre-application, select the New Pre Application link associated with the relevant program and award mechanism, and follow the prompts in eBRAP. Select the appropriate submission type (i.e., extramural or intramural). Information used to identify the pre-application will be requested at this step, including application title, keywords and research characteristics.

The incorrect selection of submission type will delay processing.

If an error was made in selecting extramural versus intramural and the pre-application submission deadline has passed, the PI or Business Official must contact the eBRAP Help Desk to request a change in designation prior to full application submission.

Once a new pre-application is created, eBRAP will assign a unique eBRAP log number. The eBRAP log number remains with the application through the entire application and review process, and throughout the life of the award if the project is recommended for funding. Applicants should use this log number when referencing the application.

The pre-application consists of the following components, organized in eBRAP by separate tabs:

Summary Tab: This tab displays the information previously entered for the pre‐application, such as application title, PI, Business Official, performing organization, contracting organization, etc. As the steps of the pre‐application are completed, additional information will display on this tab.

Tab 1 � Application Information: This tab is prepopulated with information provided when creating a new pre-application. Prepopulated information can be changed in this tab, including the application submission type. Enter additional information as prompted.

Tab 2 � Application Contacts: Enter/update contact information for the PI and the Business Official responsible for sponsored program administration. For extramural applications, this will be the �Person to be contacted on matters involving this application� in Block 5 of the Grants.gov SF424 (R&R) Form. The Business Official must be either selected from the eBRAP list or invited to allow the pre-application to be submitted. If the Business Official cannot be found in eBRAP, an invitation must be sent to them to register in eBRAP. The invitation to register must be sent prior to the pre-application deadline, but the Business Official has until the full application deadline to complete the registration. This registration is required for the Business Official to view, modify, and verify the application in eBRAP after submission.

Select the performing organization (site/organization at which the PI will perform the proposed work) and the contracting organization (recipient organization financially responsible for the award). The organization(s) must be either selected from the options available in eBRAP or invited in order for the pre-application to be submitted.

It is recommended that applicants identify an Alternate Submitter in the event that assistance with pre-application submission is needed.

Tab 3 � Collaborators and Key Personnel: Enter the name, organization, and role of all collaborators and key personnel associated with the application, including partnering PI(s), if applicable.

No member of the Programmatic Panel may be named as a Collaborator or Key Personnel for the proposed research project, nor found to have assisted in the pre-application or application processes. Refer to the specific program announcement for a link to the list of Programmatic Panel members.

Tab 4 � Conflicts of Interest: To avoid conflicts of interest during the screening and review processes, list all individuals, other than collaborators and key personnel, who may have a conflict of interest in the review of the application. Include individuals with whom the PI has a personal or professional relationship.

Tab 5 � Pre-Application Files: Upload all components as individual PDF files as specified in the program announcement. Pre-applications that have components exceeding the specified page limits may be rejected, or excess pages may be deleted from the file(s). Refer to the specific program announcement for detailed instructions. Documents should conform to the formatting guidelines outlined in Appendix 2.

Tab 6 � Submit Pre-Application: Enter your eBRAP password and click the Submit button. Click the Confirm Submission button to complete the pre-application submission. This finalizes the pre-application submission process.

Following completion of pre-application submission, the status of the pre-application in eBRAP will change from DRAFT to SUBMITTED and a confirmation email will be sent to the PI and the named Business Official.

The pre-application is not submitted until Tab 6 is complete. Pre-applications not submitted remain in DRAFT status. An applicant with a pre-application in DRAFT status after the pre-application submission deadline is ineligible to submit a full application. There is no grace period.

IV. FULL APPLICATION SUBMISSION THROUGH GRANTS.GOV

A. Grants.gov Registration

To apply through Grants.gov, an organization, foreign or domestic, must first complete the Grants.gov registration process. Allow up to eight weeks for the completion of the Grants.gov registration process. Registering early is advised.

Foreign organizations doing business outside of the United States must also fulfill any/all supplementary requirements for doing business with the U.S. government. If business is conducted with the federal government on a continuing basis, it is likely that some of the required actions have already been completed. Detailed information, links, automated tools, and checklists are available at the Grants.gov Quick Start Guide for Applicants page.

The following steps are required as part of the Grants.gov registration process:

1. Obtain Unique Entity Identifier from System for Award Management

The applicant organization must be registered as an Entity in the System for Award Management (SAM.gov) and receive confirmation of an Active status before submitting an application through Grants.gov. All federal awards, including but not limited to contracts, grants, and cooperative agreements, must use the unique entity identifier (UEI) generated by the SAM.

The SAM validates organization information and electronically shares the secure and encrypted data with federal agencies� finance offices to facilitate paperless payments through electronic funds transfer. An organization must identify an Accounts Receivable point of contact (POC), an electronic business (E-Biz) POC, and a government business POC during the SAM registration process. Entity registrations in SAM have an annual expiration. Verify the status of your organization�s entity registration in the SAM well in advance of the application submission deadline. If your organization does not have either an Employer Identification Number (EIN) or Tax Identification Number (TIN), allow at least two weeks to receive this information from the U.S. Internal Revenue Service. Allow several weeks to complete the entire SAM registration process.

Additional information and step-by-step registration directions are detailed in the SAM User Guide and other U.S. General Services Administration (GSA) training materials at the SAM.gov Help page.

Applications will be rejected by Grants.gov if: (1) the organization�s entity registration in SAM is not active; or (2) during the SAM registration process, the organization did not answer �Yes� when asked �Do you want to be eligible for grants and other federal assistance?�

2. Obtain a Commercial and Government Entity Code

The applicant organization must have a commercial and government entity (CAGE) code. The Defense Logistics Information Service in Battle Creek, Michigan, is the only authorized source of CAGE codes. CAGE codes will be assigned to registrants as their SAM registration advances through the validation process. Foreign registrants in the SAM must be assigned a North Atlantic Treaty Organization CAGE code (NCAGE). An NCAGE code can be obtained by

contacting the National Codification Bureau of the country where the organization is located or by visiting CAGE. On average, CAGE code or NCAGE code validation in the SAM occurs within three business days after the EIN or TIN is validated.

3. Register an AOR

An AOR is the Business Official designated as a member of the Grants.gov Workspace grant team who is authorized to submit the completed Workspace full application package. At the time of application submission to Grants.gov, the AOR certifies that, to the best of their knowledge, all information provided in the application is current, accurate and complete. For applications submitted through Grants.gov, the name of the AOR submitting the application is inserted into the application�s signature line, serving as the electronic signature.

An AOR must first register with the Grants.gov credential provider at Grants.gov to obtain a username and password. PIs do not register with Grants.gov. Once an AOR has completed the registration process, Grants.gov will notify the E-Biz POC of the registration; an individual may serve as both the E-Biz POC and the AOR. The E-Biz POC must then log in to Grants.gov and assign and authorize the appropriate roles, giving the AOR permission to complete and submit applications on behalf of the organization. After the E-Biz POC approves an AOR, Grants.gov will send the AOR a confirmation email.

Individuals who make legally binding commitments on behalf of an organization must be authorized as AORs by the E-Biz POC. This step, often overlooked by applicants, is crucial for valid and timely submissions.

4. Create Grants.gov Workspace

Applicants must create a Grants.gov Workspace, which allows the application components to be completed online and routed through the applicant organization for review prior to submission. Once the Workspace has been created, participants (grant team members) can be added, and the required forms can be completed and reviewed before submitting. Specific information regarding the application process through Grants.gov Workspace is available on the Grants.gov How to Apply For Grants page.

Each application submission must include the completed application package of forms associated with the specific funding opportunity in Grants.gov.

Applicants who prepare the application outside Workspace must download the individual PDF forms from Grants.gov, complete and save the forms, and upload them to Workspace. Ensure a version of Adobe Acrobat Reader that is compatible with Grants.gov is used to download, complete and submit grant applications. If multiple users are completing Workspace PDF forms, it is recommended that the same version of Adobe Acrobat Reader software be used by each user to avoid version compatibility issues. It is the applicant�s responsibility to verify their Adobe software�s compatibility with Grants.gov.

The CDMRP cannot make allowances/exceptions to its policies for submission problems encountered by the applicant organization using system-to-system interfaces with Grants.gov.

B. Content and Form of Full Application Submission � Grants.gov

(a) SF424 (R&R) � Application for Federal Assistance Form

All appropriate information must be entered into this form to allow for auto-population of subsequent forms in the Grants.gov application package.

� Block 1 � Type of Submission. For original submissions, select the Application box. For changes that must be made after the original submission, the complete Grants.gov application package must be resubmitted with the Changed/Corrected Application box selected.

� Block 2 � Date Submitted. Enter the date the application is submitted.

Applicant Identifier. Enter the submitting organization�s Control Number, if applicable. If there is no Organization Control Number, leave this field blank.

� Block 3 � Date Received by State and State Application Identifier. Not applicable.

� Block 4a � Federal Identifier. Enter the eBRAP log number assigned during pre-application submission.

Entering the eBRAP log number in Block 4a is a critical step to link the pre-application to the full application.

� Block 4b � Agency Routing Identifier. Not applicable.

� Block 4c � Previous Grants.gov Tracking ID. For changed/corrected applications, enter the Grants.gov Tracking Number for the original application.

� Block 5 � Applicant Information. Enter the information for the applicant organization. The �Person to be contacted on matters involving this application� is the Business Official.

� Block 6 � Employer Identification. Enter the EIN or TIN as assigned by the U.S. Internal Revenue Service. If applying from an organization outside the United States, enter
44-4444444.

� Block 7 � Type of Applicant. Enter the information for the applicant organization.

� Block 8 � Type of Application. Select New for all submissions. Indicate whether the application is, or will be, submitted to other agencies.

� Block 9 � Name of Federal Agency. Populated by Grants.gov.

� Block 10 � Catalog of Federal Domestic Assistance Number. Populated by Grants.gov.

� Block 11 � Descriptive Title of Applicant�s Project. Enter the same project title as used for the pre-application.

� Block 12 � Proposed Project. Enter the estimated start and end dates for the project. Actual start and end dates will be determined during negotiations if the application is recommended for funding.

� Block 13 � Congressional District of Applicant. Find your congressional district at the U.S. Census My Congressional District page. If the applicant organization is outside the United States, enter 00000.

� Block 14 � Project Director/Principal Investigator Contact Information. Enter information for the individual PI responsible for the overall scientific and technical direction of the application. If outside the United States, select the appropriate country from the drop-down menu.

� Block 15 � Estimated Project Funding. Enter the total funds (direct + indirect costs) requested for the entire performance period of the project. These figures should match those provided in the Research & Related Budget Form.

� Block 16 � Is Application Subject to Review by State Executive Order 12372 Process? Select option b., �NO, program is not covered by E.O. 12372.�

� Block 17 � Complete Certification. Select the �I agree� checkbox to provide the required certifications and assurances. By checking �I agree� on the SF424 (R&R) Form in block 17, you agree to abide by the following:

○ By signing this application, I certify: (1) to the statements contained in the list of certifications; and (2) that the statements herein are true, complete and accurate to the best of my knowledge. I also provide the required assurances and agree to comply with any resulting terms if I accept an award. I am aware that any false, fictitious, or fraudulent statements or claims may subject me to criminal, civil or administrative penalties. Refer to 18 USC 1001, the Statements or Entries Generally section of the Crimes and Criminal Procedure.

○ By signing this application, I certify the proposing entity is in compliance with Section 223(a) of the William M. (Mac) Thornberry National Defense Authorization Act for Fiscal Year 2021 which requires that: (a) the PI and other key personnel certify that the current and pending support provided on the proposal is current, accurate and complete; (b) agree to update such disclosure at the request of the agency prior to the award of support and at any subsequent time the agency determines appropriate during the terms of the award; (c) the PI and other key personnel have been made award of the requirements under Section 223(a)(1) of this Act. Refer to 42 USC 6605(a), the Disclosure Requirement subsection of Disclosure of Funding Sources in Applications for Federal Research and Development Awards.

○ Compliance with the National Policy Requirements noted in Appendix 8.

� Block 18 � SFLLL (Disclosure of Lobbying Activities) or Other Explanatory Documentation. If applicable, complete and attach Standard Form LLL (SFLLL) to disclose lobbying activities pursuant to 31 USC 1352, Limitation on Use of Appropriated Funds to Influence Certain Federal Contracting and Financial Transactions.

� Block 19 � Authorized Representative. Enter the contact information for the applicant AOR organization�s authorized representative. The Signature of Authorized Representative is automatically completed upon submission of the Grants.gov application package.

� Block 20 � Pre-Application. Not applicable.

� Block 21 � Cover Letter Attachment. Not applicable.

If a revised Project Narrative or Research & Related Budget Form is needed, an updated Grants.gov application package must be submitted via Grants.gov as a �Changed/Corrected Application� with the previous Grants.gov Tracking ID entered in Block 4.c. of the SF424 (R&R) Form prior to the full application submission deadline.

(b) Attachments Form

Grants.gov does not validate for the presence of attachments on the Attachments Form.

Each attachment in the Attachments Form must be uploaded as an individual PDF file in accordance with the formatting guidelines listed in Appendix 2. For all attachments, ensure that the file names are consistent with the guidance in the program announcement and below. Grants.gov will reject attachments with file names longer than 50 characters or incompatible file names that contain characters other than the following: A-Z, a-z, 0-9, underscore, hyphen, space, period, parenthesis, curly braces, square brackets, ampersand, tilde, exclamation point, comma, semi colon, apostrophe, at sign, number sign, dollar sign, percent sign, plus sign and equal sign. Grants.gov suggests limiting the file size of the entire grant application package including all the attachments to 200MB.

Do not password protect any files of the application package.

All documents that require signatures must be signed. Both electronic and hand signatures will be accepted. Any document that is signed by hand should be scanned at a resolution of 100-150 dots per inch.

For specific instructions regarding application attachments, attachment numbers, content, and page limits, refer to the program announcement. Attach each as a separate PDF file, named as indicated in the announcement.

The following must be included as attachments unless otherwise stated in the funding opportunity:

� Attachment: Project Narrative: Attach as �ProjectNarrative.pdf�. The Project Narrative is the main body of the application.

� Attachment: Supporting Documentation: Combine and attach as a single PDF file named �Support.pdf�. Submitting material that is not requested may be viewed as an attempt to gain an unfair competitive advantage; such material will be removed, or the application may be administratively withdrawn. Letters of support not requested in the program announcement, such as those from members of Congress, will be removed from the application package.

A complete list and descriptions of required Supporting Documentation is included in the program announcement.

� Attachment: Technical Abstract: Attach as �TechAbs.pdf�. Abstracts of all funded research projects will be posted on the CDMRP website. Do not include proprietary or confidential information. Use only characters available on a standard QWERTY keyboard. Spell out all Greek letters, other non-English letters, and symbols. Graphics are not allowed.

� Attachment: Lay Abstract: Attach as �LayAbs.pdf�. Abstracts of all funded research projects will be posted on the CDMRP website. Do not include proprietary or confidential information. Do not duplicate the technical abstract. Use only characters available on a standard QWERTY keyboard. Spell out all Greek letters, other non-English letters, and symbols. Graphics are not allowed.

� Attachment: Statement of Work: Attach as �SOW.pdf�. The SOW is an outline of the proposed research project that includes the specific aims, proposed tasks, and project milestones that will be accomplished during the award period of performance. All study site locations should be listed, including the country(s) where DOD-funded research will be performed. The SOW should contain sufficient detail to be informative as a stand-alone document, and there is no limit to the number of specific aims, tasks, or subtasks that are described within the SOW page limit. Applicants are strongly encouraged to use the suggested SOW format stated in the program announcement. Templates for SOW formats are available on the eBRAP Funding Opportunities and Forms page along with Examples for assembling statements of work.

� Attachment: Suggested Intragovernmental/Intramural Budget Form, if applicable: Attach as �IGBudget.pdf�. If an intramural DOD organization will collaborate in the performance of the project, complete a separate Suggested Intragovernmental/Intramural Budget Form for each intramural DOD organization involved in the project and upload as a single document. Detailed instructions for completing the Suggested Intragovernmental/Intramural Budget Form are provided in Section V, Full Application Submission Through eBRAP.

C. Additional Application Materials

(a) Research & Related Personal Data

Each application must include this form with the name fields of the Project Director (PD)/PI and any Co-PD(s)/Co‑PI(s) completed; however, provision of the demographic information in the form is voluntary. If completing the form for multiple individuals, each Co-PD/Co-PI can be added by selecting the Next Person button. The demographic information, if provided, will be used for statistical purposes only and will not be made available to reviewers. Applicants who do not wish to provide information should check or select the �Do not wish to provide� option.

(b) Research & Related Senior/Key Person Profile (Expanded)

Complete a Profile for each person who will contribute in a substantive, meaningful way to the scientific development or execution of the proposed research project, including the provision of degree information. All fields marked with an asterisk are required. For the application PI, in the �PROFILE � Project Director/Principal Investigator� section, enter the PI�s User Name provided by eBRAP into the data field labeled �Credential, e.g., agency login� (Green Box, Figure 1). Additional Senior/Key persons can be added by selecting the Next Person button.

A biographical sketch and full description of each PI and Senior/Key Person�s current/pending support information must be attached to the individual�s Profile in the Attach Biographical Sketch and Attach Current & Pending Support fields, respectively.

Figure 1. PI�s eBRAP User Name

Biographical Sketch: This file must be titled �Biosketch_LastName.pdf� where �LastName� is the last name of the PI or Senior/Key Person.

Biographical sketches must conform to the federal wide Biographical Sketch Common Form. Applicants may use the instructions provided below or may use a pdf form created in SciENcv �for the National Institutes of Health (NIH) or the U.S. National Science Foundation (NSF).

The following provides instructions for submitting the biographical sketch for each individual identified as a Senior/Key person on the proposal. These instructions serve as CDMRP's implementation of the Biographical Sketch Common Form developed by the National Science and Technology Council�s Subcommittee on Research Security. A complete list of terms and definitions is available in the NSPM-33 Implementation Guidance.

Consistent with NSPM-33, individuals are required to disclose contracts associated with participation in programs sponsored by foreign governments, instrumentalities, or entities, including foreign government-sponsored talent recruitment programs. Further, if an individual receives direct or indirect support that is funded by a foreign government-sponsored talent recruitment program, even where the support is provided through an intermediary and does not require membership in the foreign government-sponsored talent recruitment program, that support must be disclosed. Individuals must also report other foreign government-sponsored or affiliated activities. In accordance with 42 USC 19232, the Malign Foreign Talent Recruitment Program Prohibition Statute, individuals are prohibited from being a party in a malign foreign talent recruitment program.

The table entitled NSPM-33 Implementation Guidance Pre- and Post-award Disclosures Relating to the Biographical Sketch and Current and Pending (Other) Support provides helpful reference information regarding pre-award and post-award disclosures. The table includes the types of activities to be reported, where such activities must be reported in the proposal, as well as when updates are required in the proposal and award lifecycle. A final column identifies activities that are not required to be reported.

Provide only the information requested below in the order it is listed. All elements are required unless otherwise noted. There is no page or character limit to this section of the proposal.

(1) Identifying Information

(i) Name: Enter the name of the Senior/Key person (Last name, First name, Middle name, including any applicable suffix).

(ii) Open Researcher and Contributor ID (ORCID) of the Senior/Key Person (optional): Enter the ORCID of the Senior/Key person. The ORCID is a unique, open digital identifier that distinguishes the individual from every other researcher with the same or a similar name.

(iii) Position Title: Enter the current position title of the Senior/Key person.

(2) Organization and Location

(i) Name: Enter the name of the primary organization of the Senior/Key person.

(ii) Location: Enter the City, State/Province, and Country where the primary organization is located. If the State/Province is not applicable, enter N/A.

(3) Professional Preparation

Provide a list of the Senior/Key person's professional preparation (e.g., education and training), listed in reverse chronological order by start date. Include all postdoctoral and fellowship training, as applicable, listing each separately. Also include the baccalaureate degree or other initial professional education.

For each entry provide:

� the name of the organization

� the location of the organization: Enter the City, State/Province, and Country where the organization is located. If the State/Province is not applicable, enter N/A.

� the degree received (if applicable)

� the start date of the degree or fellowship program

� the month and year the degree was received (or expected receipt date)

� the field of study

(4) Appointments and Positions

A list, in reverse chronological order by start date, of all the individual�s academic, professional, or institutional appointments and positions, beginning with the current appointment (including the associated organization and location). Appointments and positions include any titled academic, professional, or institutional position whether or not remuneration is received, and whether full-time, part-time, or voluntary (including adjunct, visiting or honorary).

Senior/Key persons must only identify all domestic and foreign professional appointments and positions outside of the primary organization for a period up to three years from the date the applicant submits the application to CDMRP for funding consideration.

For each entry provide:

� Start date: YYYY

� End date: YYYY

� Appointment or Position Title

� Name of organization

� Department (if applicable)

� Location of organization: City, State/Province, Country

(5) Products

Provide a list of products that demonstrate the individual�s qualifications to carry out the project as proposed. It is up to the individual to determine how to best organize this listing to demonstrate their ability to carry out the project. Acceptable products must be citable and accessible, including but not limited to:

� publications, conference papers and presentations

� website(s) or other Internet site(s)

� technologies or techniques

� inventions, patents, patent applications and/or licenses

� other products, such as data, databases, or datasets, physical collections, audio or video products, software, models, educational aids or curricula, instruments or equipment, research material, interventions (e.g., clinical or educational), or new business creation

Each product must include full citation information including:

� names of authors

� product title

� date of publication or release

� website URL

� other persistent identifier (if available)

� other relevant citation information (e.g., in the case of publications, title of enclosing work such as journal or book, volume, issue, pages)

If any of the items specified above is not applicable, enter N/A.

Senior/Key personnel who wish to include publications in the products section of the Biographical Sketch that include multiple authors may, at their discretion, choose to list one or more of the authors and then "et al" in lieu of including the complete listing of authors� names.

(6) Certification

Each Senior/Key person is required to complete the following certifications regarding the information provided in their Biographical Sketch:

I certify that the information provided is current, accurate, and complete. This includes but is not limited to information related to domestic and foreign appointments and positions.

I also certify that, at the time of submission, I am not a party in a malign foreign talent recruitment program.

Misrepresentations and/or omissions may be subject to prosecution and liability pursuant to, but not limited to, 18 U.S.C. �� 287, 1001, 1031 and 31 U.S.C. �� 3729-3733 and 3802.

Signature and Date: To be acceptable, the date of the signature must be within the past 12 months from when the document is submitted.

Current/Pending Support: This file must be titled �Support_LastName.pdf� where �LastName� is the last name of the PI or Senior/Key Person.

Current and pending support documentation must conform to the federal wide format. Applicants may use the instructions provided below, or may use a pdf form created in SciENcv for the NIH or NSF.

The following provides instructions for submitting current and pending (other) support information for each individual identified as a Senior/Key person on a CDMRP application. These instructions serve as the CDMRP's implementation of the Current and Pending (Other) Support Common Form. A complete list of terms and definitions is available in the NSPM-33 Implementation Guidance.

A separate submission must be provided for each proposal and active project, as well as in-kind contributions using the instructions and format specified below.

Consulting activities must be disclosed under the Proposals/Active Projects section of the form when any of the following scenarios apply:

o The consulting activity will require the Senior/Key person to perform research as part of the consulting activity.

o The consulting activity does not involve performing research, but is related to the Senior/Key person�s research portfolio and may have the ability to impact funding, alter time or effort commitments, or otherwise impact scientific integrity.

o The consulting entity has provided a contract that requires the Senior/Key person to conceal or withhold confidential financial or other ties between the Senior/Key person and the entity, irrespective of the duration of the engagement.

Consistent with NSPM-33, individuals are required to disclose contracts associated with participation in programs sponsored by foreign governments, instrumentalities, or entities, including foreign government-sponsored talent recruitment programs. Further, if individuals receive direct or indirect support that is funded by a foreign government-sponsored talent recruitment program, even where the support is provided through an intermediary and does not require membership in the foreign government-sponsored talent recruitment program, that support must be disclosed. Individuals must also report other foreign government sponsored or affiliated activities. In accordance with 42 USC 19232, the Malign Foreign Talent Recruitment Program Prohibition Statute, individuals are prohibited from being a party in a malign foreign talent recruitment program.

The table entitled NSPM-33 Implementation Guidance Pre- and Post-award Disclosures Relating to the Biographical Sketch and Current and Pending (Other) Support provides helpful reference information regarding pre-award and post-award disclosures. The table includes the types of activities to be reported, where such activities must be reported in the application, as well as when updates are required in the application and award lifecycle. A final column identifies activities that are not required to be reported.

Note that there is no page limitation for this section of the application, though some fields have character limitations for consistency and equity. Provide only the information requested in the order it is listed. All elements are required unless otherwise noted.

(1) Identifying Information

(i) Name: Enter the name of the Senior/Key person (Last name, First name, Middle name, including any applicable suffix).

(iii) Position Title: Enter the current position title of the Senior/Key person.

(2) Organization and Location

(i) Name: Enter the name of the primary organization of the Senior/Key person.

(ii) Location: Enter the City, State/Province, and Country where the primary organization is located. If the State/Province is not applicable, enter N/A.

(3) Proposals/Active Projects

In this section, disclose ALL proposals and active projects in accordance with the definitions for current and pending (other) support.

(i) Title: Enter the title of each project/active proposal being reported.

(ii) Status of Support: Select the appropriate status type as defined below:

Current � all active projects, or projects with ongoing obligations, from whatever source irrespective of whether such support is provided through the proposing organization or is provided directly to the individual.

Pending � any proposal that is being considered for funding from a potential funding organization (including this proposal) irrespective of whether such support is provided through the proposing organization or is provided directly to the individual.

(iii) Proposal/Active Award Number (if available): Enter the applicable proposal/active award number for each proposal and/or award, if available.

(iv) Source of Support: Identify the entity for each proposal and/or active project that is providing the support. Include all Federal, State, Tribal, territorial, local, foreign, public or private foundations, non-profit organizations, industrial or other commercial organizations, or internal funds allocated toward specific projects.

(v) Primary Place of Performance: Identify the primary location where the proposal and/or active project is being executed. Enter the City, State/Province, and Country where the organization is located. If the State/Province is not applicable, enter N/A.

(vi) Proposal/Active Project Start Date: Indicate the start date (MM/YYYY) of the project, as proposed/awarded.

(vii) Proposal/Active Project End Date: Indicate the end date (MM/YYYY) of the project, as proposed/awarded.

(viii) Total Anticipated Proposal/Project Amount: Enter the total award amount for the entire period of performance, inclusive of indirect costs, rounded to the nearest dollar. If the dollar value is not readily ascertainable, a reasonable estimate should be provided. If the support is in a foreign country's currency, convert to U.S. dollars at time of submission.

(ix) Person-Month(s) (or Partial Person-Months) Per Year Devoted to the Proposal/Active Project: Enter how much time the individual anticipates is necessary to complete the scope of work on the proposal and/or active project. Enter the number of person-months (even if unsalaried) for the current budget period and enter the proposed person-months for each subsequent budget period. If the time commitment is not readily ascertainable, a reasonable estimate should be provided.

(x) Overall Objectives: Provide a brief statement of the overall objectives of the proposal/active project. This field is limited to 1500 characters.

(xi) Statement of Potential Overlap: Enter a description of the potential overlap with any pending proposal or active foreign or domestic project and this proposal in terms of scope, budget, or person-months planned or devoted to the project by the individual. If there is no potential overlap, enter "none" in this field.

(4) In-Kind Contributions

In this section, disclose ALL in-kind contributions with an estimated dollar value of $5000 or more and that require a commitment of the individual's time. An in-kind contribution is a non-cash contribution provided by an external entity that directly supports the individuals' research and development efforts. An in-kind contribution may include but is not limited to: real property; laboratory space; equipment; data or data sets; supplies; other expendable property; goods and services; employee or student resources. In-kind contributions with an estimated value of less than $5000 need not be reported.

(i) Status of Support: Select the appropriate status type as defined below:

Current � all in-kind contributions obligated from whatever source irrespective of whether such support is provided through the proposing organization or is provided directly to the individual.

Pending � all in-kind contributions currently under consideration from potential funding organizations irrespective of whether such support is provided through the proposing organization or is provided directly to the individual.

(ii) Receipt (or Anticipated Receipt) Date of In-Kind Contribution: Enter the receipt date (or anticipated receipt date) of the in-kind contribution.

(iii) Source of Support: Identify the entity (entities) that is providing the in-kind contribution. Include, for example, Federal, State, Tribal, territorial, local, foreign, public or private foundations, non-profit organizations, industrial or other commercial organizations, or internal funds allocated toward specific projects.

(iv) Summary of In-Kind Contribution(s): Enter a summary of the in-kind contribution not intended for use on the proposal/active project.

(v) Person-Month(s) (or Partial Person-Months) Per Year Devoted to the In-Kind Contribution: Enter how much time the individual anticipates is necessary to complete the scope of work associated with use of the in-kind contribution. Enter the number of person-months (even if unsalaried) for the current budget period and enter the proposed person-months for each subsequent budget period. If there is no associated time commitment, the in-kind contribution need not be reported.

(vi) U.S. Dollar Value of In-Kind Contribution: Enter the U.S. dollar value of the in-kind contribution with an estimated value of $5000 or more. If the dollar value is not readily ascertainable, a reasonable estimate should be provided. If the support is in a foreign country's currency, convert to U.S. dollars at time of submission rounded to the nearest dollar.

(vii) Overall Objectives: Provide a brief statement of the overall objectives of the in-kind contribution(s). This field is limited to 1500 characters.

(viii) Statement of Potential Overlap: Enter a description of the potential overlap with any current or pending foreign or domestic in-kind contribution and this proposal in terms of scope, budget, or person-months planned or devoted to the project by the individual. If there is no overlap, enter "none" in the field.

(5) Certification

Each Senior/Key person is required to complete the following certifications regarding the information provided in their Current and Pending (Other) Support:

I also certify that, at the time of submission, I am not a party in a malign foreign talent recruitment program.

Misrepresentations and/or omissions may be subject to prosecution and liability pursuant to, but not limited to, 18 U.S.C. ��287, 1001, 1031 and 31 U.S.C. ��3729-3733 and 3802.

Signature and Date: To be acceptable, the date of the signature must be within the past 12 months from when the document is submitted.

(c) Research & Related Budget

An estimate of the total proposed research project cost, with a breakdown of all cost categories for each year of the project, must be submitted using the Grants.gov Research & Related Budget Form. For limits on funding amounts, types of costs, and period of performance, refer to the program announcement. A budget justification for the entire period of performance must be uploaded to Section L in the Budget Period 1 portion of the Research & Related Budget Form. The budget and budget justification should include sufficient detail for the government to determine whether the proposed costs are allowable, allocable, and reasonable for the proposed research. At the time of application submission to Grants.gov, the AOR is certifying to the best of their knowledge that all costs are current, accurate and complete. The government reserves the right to request a revised budget and budget justification and/or additional information.

If the budget fails eBRAP validation or needs to be modified, an updated Grants.gov application package must be submitted via Grants.gov as a �Changed/Corrected Application� with the previous Grants.gov Tracking ID prior to the application submission deadline.

Budget Regulations and Restrictions:

� Administrative and Cost Principles: Recipients will be required to comply with the following, as applicable:

○ Code of Federal Regulations, Title 2, Part 200, or 2 CFR 200, Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards, as implemented by Chapter XI of Title 2 CFR.

○ Provisions of Chapter I, Subchapter C of 32 CFR, DOD Grant and Agreement Regulations, specifically: (1) 32 CFR 26, Governmentwide Requirements for Drug-Free Workplace (Financial Assistance); (2) 32 CFR 28, New Restrictions on Lobbying; and (3) 32 CFR 34.16, Audits; and also 2 CFR, Chapter XI, Parts 1100-1199, Federal Agency Regulations or Grants and Agreements for the Department of Defense.

○ Federal Acquisition Regulation (FAR) Part 31, Contract Cost Principles and Procedures.

It is prohibited to charge a fee or profit to an assistance agreement, either by the recipient/awardee or subrecipient/subawardee.

� Cost of Preparing Applications: The cost of preparing applications in response to a program announcement is not considered an allowable direct charge to any resultant award. However, the cost of preparing applications may be an allowable cost that can be included in the indirect/facilities and administrative (F&A) cost as specified in the organization�s applicable cost principles.

� Currency: All costs must be entered in U.S. dollars.

� Budget Instructions: Complete Sections A through L of the Research & Related Budget Form following the instructions below. Begin by entering the organizational UEI

number, Budget Type, Name of Organization, and anticipated start and end dates. Funds requested should be specific to the proposed research project and should be consistent with the work outlined in the Project Narrative and SOW.

Ensure that the UEI number is entered accurately or Grants.gov will reject the application.

Section A: Senior/Key Person

Prefix; First, Middle, and Last Name; and Suffix: Beginning with the PI, list all Senior/Key persons from the applicant organization who will be involved in the proposed research project, whether or not salaries are requested. Include all investigators, research associates, etc. If applicable, all investigators outside the applicant organization should be included on the Research & Related Subaward Budget Attachment(s) Form. Consultant costs should be listed under Section F.3 of the Research & Related Budget Form (Other Direct Costs, Consultant Services).
Base Salary: Enter the current annual base salary (based on a full-time appointment) for each individual listed for the proposed research project. Establish labor costs using current labor rates or salaries. Labor rates or salaries may not be increased as a result of receiving an award. Any proposed increases in rates or salaries over the period of the award must be consistent with the applicable cost principles and organization�s estimating procedures. For most federal agencies, funding cannot be applied toward federal salaries and therefore these salaries should not be included in the requested budget.
Level of Effort (Calendar, Academic and Summer Months): For each Senior/Key person, including unpaid personnel, demonstrate the level of effort by listing the number of months to be devoted to the proposed research project in the appropriate box.
Requested Salary: Enter the amount of salary requested for this budget period.
Fringe Benefits: Enter the fringe benefits requested for each individual in accordance with organizational guidelines. If the application is recommended for funding, the organization will be required to provide documentation to support the fringe benefits (e.g., the current U.S. Department of Health and Human Services [DHHS] Rate Agreement, other federally approved rate agreement, or other policy document).
Funds Requested: Enter the total funds requested for each Senior/Key person listed for the proposed research project.
Project Role: Identify the role of each Senior/Key person listed.

Section B: Other Personnel

Number of Personnel: For each project role category, indicate the number of personnel for the proposed research project, including unpaid personnel.
Project Role: Identify each project role category.
Level of Effort (Calendar, Academic and Summer Months): For each project role category, demonstrate the level of effort by listing the number of months to be devoted to the proposed research project in the appropriate box.
Requested Salary: Enter the amount of salary requested for this budget period. For most federal agencies, funding cannot be applied toward federal salaries and therefore these salaries should not be included in the requested budget.
Fringe Benefits: Enter the fringe benefits requested for each project role category in accordance with organizational guidelines. If the application is recommended for funding, the organization will be required to provide documentation to support the fringe benefits (e.g., the current DHHS Rate Agreement, other federally approved rate agreement, or other policy document).
Funds Requested: Enter the total funds requested for each project role category listed for the proposed research project.

Section C: Equipment Description. Equipment is tangible personal property (including information technology systems) having a useful life of more than one year and a per-unit acquisition cost that equals or exceeds the lesser of: (1) $5,000; or (2) the recipient�s or the subrecipient�s capitalization threshold for financial statement purposes. Applicant organizations are encouraged to provide all equipment necessary to conduct the proposed research project.

Section D: Travel. Enter the total funds requested for travel. Applicants are responsible for budgeting all costs associated with travel, including airfare, hotel, etc., associated with the trip. Refer to the specific program announcement for instructions regarding required travel and/or travel limitations.

Funds to an extramural organization may not be used to cover travel costs for DOD military and civilian employees. All approved travel costs for DOD military and civilian employees will be paid by the government through a direct fund transfer. Proposed travel costs for DOD military and civilian employees should be included on the Suggested Intragovernmental/Intramural Budget Form.

Section E: Participant/Trainee Support Costs. Enter the funds requested for tuition/fees/health insurance, stipends, travel, subsistence and other costs. Include the number of participants/trainees that the requested costs will support.

Section F: Other Direct Costs

Materials and Supplies: Materials and supplies are all tangible property, including a computing device, acquired under an award that does not meet the definition of equipment.
Publication Costs: Estimate the costs of publishing and reporting research results, including direct charges for clerical preparation, illustrations, reprints and distribution.
Consultant Services: Include the total funds requested for consulting services.
Automated Data Processing (ADP)/Computer Services: Include the cost of computer services, including computer-based retrieval of scientific, technical and education information.
Subaward/Consortium/Contractual Costs: Include the total funds requested for: (1) all subaward/consortium organization(s) proposed for the research project (direct and indirect costs); and (2) any other contractual costs proposed for the research project. This amount should be supported in the subaward/consortium/contractual costs provided in the Research & Related Subaward Budget Attachment(s) Form, or in the Suggested Intragovernmental/Intramural Budget Form if the subaward is to an intramural organization. For further instructions, refer to Research & Related Subaward Budget Attachment(s) Form.

All direct and indirect costs of any subaward, including intragovernmental/intramural collaborators, must be included in the direct costs of the primary award.

Equipment or Facility Rental/User Fees: List proposed equipment or facility rental/user fees.
Alterations and Renovations: Alteration and renovation (A&R) costs can be requested if the costs are essential to accomplish the objectives of the research project and are a minor portion of the overall budget. Costs for the construction of facilities are not allowable.
Other Expenses: Use lines 8-17 to itemize other anticipated direct costs as needed (e.g., communication costs, organizationally provided core services). If the proposed research project includes research-related human subjects costs, the requested funds are strictly limited to expenses specifically associated with the proposed research project.

Section G: Direct Costs. State the total direct costs (i.e., summation of Sections A-F) for the budget period.

The primary award (including the direct and indirect costs of any subawardees, if applicable) should not exceed the cost limit stated in the program announcement.

Section H: Indirect Costs. The indirect costs category may include F&A costs, overhead, General and Administrative (G&A), and other. The most recent federal agency approved rate(s) should be applied. If the rate(s) has been approved by other than a federal agency, indicate the source of the approval. No budget will be approved by the government using an indirect rate exceeding the organization�s negotiated rate.

In accordance with 2 CFR 200.414(f), De Minimis Rate, a nonfederal entity that does not have a current negotiated (including provisional) rate may elect to charge a de minimis rate of 10% of modified total direct costs. Costs must be consistently charged as either indirect or direct costs but may not be double-charged or inconsistently charged as both. If this methodology is chosen, it must be used consistently for all federal awards until such time as the nonfederal entity chooses to negotiate for a rate.

Organizations can also visit the websites for the DHHS, the Office of Naval Research, and the Defense Contract Audit Agency for additional information on indirect rates.

Section I: Total Direct and Indirect Costs. State the total costs (i.e., summation of Sections G and H) for the budget period.

Section J: Fee. It is prohibited to charge a fee or profit to an assistance agreement, either by the recipient/awardee or subrecipient/subawardee.

Section K: Total Costs and Fee. As it is prohibited to charge a fee or profit to an assistance agreement, the value in Section K should equal the value in Section I.

Section L: Budget Justification. Provide a clear budget justification for each item in the budget over the entire period of performance and attach as a single PDF file to Section L in the Budget Period 1 portion of the Research & Related Budget Form. It is recommended that the headings of the cost categories in the budget justification match the cost categories in the Research & Related Budget Form. Itemize direct costs for all years of the award. Organizations must provide sufficient detail and justification so the government can determine that the proposed costs are allowable, allocable, and reasonable for the proposed research effort. Applicants performing research outside of the United States should also include the cost in local currency, the rate used for converting to U.S. dollars, and justification/basis for the conversion rate used. Foreign currency exchange rates for applicants performing research outside of the United States will be determined at the time of application submission.

Personnel: Identify the role of each Senior/Key person listed and describe their specific functions in the budget justification. Identify and explain any proposed adjustments to labor rates or salaries.

Equipment: If equipment is requested, provide a detailed list showing the cost of each item and a rationale for the stated costs. The budget justification for any requested equipment must describe, as applicable: (1) special test equipment to be fabricated for specific research purposes and its cost; (2) standard equipment to be acquired and modified to meet specific requirements, including acquisition and modification costs; list separately; and (3) existing equipment to be modified to meet specific research requirements, including modification costs. Do not include as special test equipment those items of equipment that, if purchased by the recipient with recipient funds, would be capitalized for federal income tax purposes.

Travel: If travel costs are requested to attend scientific/technical meetings, include the meeting name, purpose, location, and date, if known. International travel may be requested but must be justified with additional documentation and is subject to approval by the Grants Officer. The justification should clearly confirm that the requested travel costs meet any travel requirements and/or restrictions stated in the funding opportunity.

Materials and Supplies: Include a general description of expendable material and supplies for each year. If animals are to be purchased, state the species, strain (if applicable), number to be used, cost per animal and total costs, proposed vendor, and a copy of the animal per diem cost/rate agreement. If human cell lines are to be purchased, state the source, cost and description. If a computer/software purchase is requested, include a detailed explanation for why purchase of computer/software is

required to complete the proposed research project. Include a statement verifying that the requested computer/software is not currently available for use.

Consultant Services: Independent of whether funds are requested for any proposed consultant services, include the name(s) and organizational affiliation(s) of all consultants; and include the daily consultant fee, travel expenses, nature of the consulting effort; and why consultants are required for the proposed research project.

Equipment or Facility Rental/User Fees: List the proposed equipment or facility rental/user fees, including data processing fees. Include information regarding estimated hours/units required for the proposed research project and the provider�s service rates.

Alterations and Renovations: Provide a description of the existing facility and detailed description of the requested changes. Include a justification outlining how changes directly support the proposed research. Costs for the construction of facilities are not allowable.

Other Direct Costs: Describe and justify any other requested direct cost categories.

Indirect Costs: Provide details of the direct cost base (modified total direct costs, salary and wage, or other). Identify any costs that have been excluded from the base (in accordance with the approved rate agreement). Also indicate whether the rate(s) is an on-site or off-site rate(s). If more than one rate is applicable, provide a breakdown of the calculation.

Federal Financial Plan: The CDMRP�s funding is directed by Congress on a yearly basis for each program and is obligated up front for each award as there is no guarantee of future program appropriations. Funds are available for obligation for two years from the beginning of the fiscal year of appropriation. For applications involving an intragovernmental or intramural DOD organization, include a federal financial plan in the budget justification. The plan must address how any funds transferred to the intragovernmental or intramural DOD organization will be obligated before their expiration for obligation, and how funds will be available to cover research costs over the entire award period. The plan must include the funding mechanism(s) that will be used to carry over funds between fiscal years, if applicable. The CDMRP encourages intramural DOD applicants to plan for the transfer of funding via Project Orders, where applicable. Unless otherwise stated in the funding opportunity, the CDMRP does not intend to use funds from future fiscal year(s), if appropriated, to support the award.

Foreign Collaboration Justification: Applications that propose consultant, subaward, consortium, or contractual arrangements with foreign organizations, or collaborators employed by foreign organizations/governments, are required to demonstrate how one or more of the following conditions have been met:

o The foreign organization or individual(s) employed by foreign organizations/governments contributes unique expertise, organizational capability, facilities, data resources; and/or access to a geographic location or population not generally available to investigators based in the United States (or which would require significant effort or time to duplicate) or would potentially significantly advance the health sciences in the United States.

o The foreign organization, individual(s) employed by foreign organizations/governments, or project offers significant unique health research opportunities to advance U.S. Military medicine and benefit Service Members, Veterans and their Families.

(d) Project/Performance Site Location(s) Form

Indicate the primary site where the work will be performed. If a portion of the work will be performed at any other site(s), include the name and address for each collaborating location in the data fields provided. Add more sites as necessary using the Next Site button. If more than eight performance site locations are proposed, provide the requested information in a separate file and attach it to this form. Each additional research site requesting funds will require a subaward budget.

(e) Research & Related Subaward Budget Attachment(s) Form (if applicable)

Extramural Subaward(s): Complete a separate Research & Related Budget Form, including a budget justification, for each subaward (subgrant or contract) in accordance with the instructions described above. Title each individual subaward document �Research & Related Budget� with the name of the subaward recipient organization and attach to the Research & Related Subaward Budget Attachment(s) Form.

Intramural DOD Subaward(s): Complete a separate Suggested Intragovernmental/Intramural Budget Form, including a budget justification, for each intramural subaward, using the instructions in Section VI, Full Application Submission Through eBRAP, and upload as a single document titled �IGBudget.pdf� to the Grants.gov Attachments Form.

All direct and indirect costs of any subaward must be included in the direct costs of the primary award. The primary award (including the direct and indirect costs of any subawardees) should not exceed the cost limit stated in the program announcement.

D. Submission to Grants.gov

Grants.gov strongly recommends submitting the application package at least 24-48 hours prior to the close date to provide time to correct any potential technical issues that may disrupt the application submission.

All applications must be received by the deadline indicated in the program announcement. Proof of timely submission is automatically recorded by Grants.gov. An electronic date/time stamp is generated within the system when the application is successfully received by Grants.gov. The applicant AOR will receive an acknowledgement of receipt and a Tracking Number (GRANTXXXXXXXX) from Grants.gov with the successful transmission of the application. Applicant AORs will also receive the official date/time stamp and Grants.gov Tracking Number in an email serving as proof of the application�s timely submission. The submission of a Workspace package can be tracked from the Workspace or by visiting Grants.gov and entering the Tracking Number.

E. Applicant Verification of Grants.gov Submission in eBRAP

Once the full application is submitted to Grants.gov, it is transmitted to and processed in eBRAP. At this stage, the PI and organizational representatives will receive an email from eBRAP instructing them to log into eBRAP to review, modify, and verify the full application submission. Verification is strongly recommended but not required. eBRAP will validate full application files against the specific program announcement requirements, and discrepancies will be noted in the Full Application Files tab. However, eBRAP does not confirm the accuracy of file content. It is the applicant�s responsibility to review all application components and ensure proper ordering as specified in the program announcement.

The Project Narrative and the Research & Related Budget Form cannot be changed after the application submission deadline. If either the Project Narrative or the budget fails eBRAP validation or needs to be modified, an updated full

application package must be submitted to Grants.gov prior to the full application submission deadline.

The full application submission deadline and the end of the application verification period are stated in Section 1, Basic Information About the Funding Opportunity, of the specific program announcement.

V. FULL A PPLICATION SUBMISSION THROUGH eBRAP

A. Content and Form of Full Application Submission � eBRAP

(a) eBRAP Full Application Package Components

The eBRAP full application package includes the following components, which are organized in eBRAP by separate tabs. To access these tabs, go to your My Applications page and click Start Full Application for the log number under which the pre-application was submitted.

Tab 1 � Summary: Provides a summary of the application information and copies of standard application forms.
Tab 2 � Contacts: This tab will be populated by eBRAP. Add the name of the AOR.
Tab 3 � Full Application Files: Upload each application component in eBRAP as individual PDF files. Refer to Appendix 2 for detailed formatting guidelines.
Tab 4 � Application and Budget Data: Review and edit the Proposed Project Start Date, Proposed End Date, and budget data that is pre-populated from the Budget Form.
Tab 5 � Submit/Request Approval Full Application: Once all components have been uploaded, and prior to the full application submission deadline, enter your password in the space provided next to �Enter Your Password Here� and press the Submit Full Application button. eBRAP will validate files against the program announcement requirements, and discrepancies will be noted. If no discrepancies are noted, press the

Confirm Submission button to complete the application submission. eBRAP will notify your RM/Comptroller/Task Area Manager or equivalent Business Official by email to log into eBRAP to review and approve the full application package prior to the approval deadline.

(b) Attachments

Application components for intramural submissions are identical to those mentioned above for extramural submission, unless otherwise stated below.

Upload attachments to Tab 3 � Full Application Files. Each attachment must be uploaded as an individual PDF file, unless otherwise stated. Do not password protect any files of the application package, including the Project Narrative.

The following must be included as attachments unless otherwise stated in the funding opportunity:

Attachment: Project Narrative: Attach as �ProjectNarrative.pdf�. The Project Narrative is the main body of the application.
Attachment: Supporting Documentation: Combine and attach as a single PDF file named �Support.pdf�. Submitting material that is not requested may be viewed as an attempt to gain an unfair competitive advantage; such material will be removed, or the application may be administratively withdrawn. Letters of support not requested in the program announcement, such as those from members of Congress, will be removed from the application package.

A complete list and descriptions of required Supporting Documentation is included in the broad agency announcement.

Attachment: Technical Abstract: Attach as �TechAbs.pdf�. Abstracts of all funded research projects will be posted on the CDMRP website. Do not include proprietary or confidential information. Use only characters available on a standard QWERTY keyboard. Spell out all Greek letters, other non-English letters, and symbols. Graphics are not allowed.
Attachment: Lay Abstract: Attach as �LayAbs.pdf�. Abstracts of all funded research projects will be posted on the CDMRP website. Do not include proprietary or confidential information. Do not duplicate the technical abstract. Use only characters available on a standard QWERTY keyboard. Spell out all Greek letters, other non-English letters, and symbols. Graphics are not allowed.

Attachment: SOW: Attach as �SOW.pdf�. The SOW is an outline of the proposed research project that includes the specific aims, proposed tasks, and project milestones that will be accomplished during the award period of performance. All study site locations should be listed, including the country(ies) where DOD-funded research will be performed. The SOW should contain sufficient detail to be informative as a stand-alone document and there is no limit to the number of specific aims, tasks, or subtasks that are described within the SOW page limit. Applicants are strongly encouraged to use the suggested SOW format stated in the program announcement. A suggested template for SOW format is available on the eBRAP Funding Opportunities and Forms page along with Examples for assembling statements of work.

B. Additional Application Materials

(a) Research & Related Personal Data

Each application must include this form with the name fields of the PD/PI and any Co-PD(s)/Co-PI(s) completed; however, provision of the demographic information in the form is voluntary. If completing the form for multiple individuals, each Co-PD/Co-PI can be added by selecting the Next Person button. The demographic information, if provided, will be used for statistical purposes only and will not be made available to reviewers. Applicants who do not wish to provide information should check or select the �Do not wish to provide� option.

Upload the Research & Related Personal Data Form as �PersonalData_LastName.pdf� to Tab 3 � Full Application Files.

(b) Research & Related Senior/Key Person Profile (Expanded)

Complete a Profile for each person who will contribute in a substantive, meaningful way to the scientific development or execution of the proposed research project, including the provision of degree information. All fields marked with an asterisk are required. For the application PI, in the �PROFILE � Project Director/Principal Investigator� section, enter the PI�s User Name provided by eBRAP into the data field labeled �Credential, e.g., agency login� (Green Box, Figure 2). Additional Senior/Key persons can be added by selecting the Next Person button.

Figure 2. PI�s eBRAP User Name

A biographical sketch and full description of each PI and Senior/Key Person�s previous/current/pending support information may be either attached to the Research & Related Senior/Key Person Profile (Expanded) Form or uploaded as individual files within Tab 3 � Full Application Files.

Upload the Research & Related Senior/Key Person Profile (Expanded) as �KeyPersonnel_LastName.pdf� to Tab 3 � Full Application Files.

Biographical Sketch: This file must be titled �Biosketch_LastName.pdf� where �LastName� is the last name of the PI or Senior/Key Person.

sponsored talent recruitment program, even where the support is provided through an intermediary and does not require membership in the foreign government-sponsored talent recruitment program, that support must be disclosed. Individuals must also report other foreign government-sponsored or affiliated activities. In accordance with 42 USC 19232, the Malign Foreign Talent Recruitment Program Prohibition Statute, individuals are prohibited from being a party in a malign foreign talent recruitment program.

Provide only the information requested below in the order it is listed. All elements are required unless otherwise noted. There is no page or character limit to this section of the proposal.

(1) Identifying Information

(i) Name: Enter the name of the Senior/Key person (Last name, First name, Middle name, including any applicable suffix).

(iii) Position Title: Enter the current position title of the Senior/Key person.

(2) Organization and Location

(i) Name: Enter the name of the primary organization of the Senior/Key person.

(ii) Location: Enter the City, State/Province, and Country where the primary organization is located. If the State/Province is not applicable, enter N/A.

(3) Professional Preparation

For each entry provide:

� the name of the organization

� the location of the organization: Enter the City, State/Province, and Country where the organization is located. If the State/Province is not applicable, enter N/A.

� the degree received (if applicable)

� the start date of the degree or fellowship program

� the month and year the degree was received (or expected receipt date)

� the field of study

(4) Appointments and Positions

For each entry provide:

� Start date: YYYY

� End date: YYYY

� Appointment or Position Title

� Name of organization

� Department (if applicable)

� Location of organization: City, State/Province, Country

(5) Products

� publications, conference papers and presentations

� website(s) or other Internet site(s)

� technologies or techniques

� inventions, patents, patent applications and/or licenses

Each product must include full citation information including:

� names of authors

� product title

� date of publication or release

� website URL

� other persistent identifier (if available)

� other relevant citation information (e.g., in the case of publications, title of enclosing work such as journal or book, volume, issue, pages)

If any of the items specified above is not applicable, enter N/A.

Senior/Key personnel who wish to include publications in the Products section of the Biographical Sketch that include multiple authors may, at their discretion, choose to list one or more of the authors and then "et al" in lieu of including the complete listing of authors� names.

(6) Certification

Each Senior/Key person is required to complete the following certifications regarding the information provided in their Biographical Sketch:

I certify that the information provided is current, accurate, and complete. This includes but is not limited to information related to domestic and foreign appointments and positions.

I also certify that, at the time of submission, I am not a party in a malign foreign talent recruitment program.

Misrepresentations and/or omissions may be subject to prosecution and liability pursuant to, but not limited to, 18 U.S.C. �� 287, 1001, 1031 and 31 U.S.C. �� 3729-3733 and 3802.

Signature and Date: To be acceptable, the date of the signature must be within the past 12 months from when the document is submitted.

Current/Pending Support: This file must be titled �Support_LastName.pdf� where �LastName� is the last name of the PI or Senior/Key Person.

Current and pending support documentation must conform to the federal wide format. Applicants may use the instructions provided below, or may use a pdf form created in SciENcv for NIH or NSF.

The following provides instructions for submitting current and pending (other) support information for each individual identified as a Senior/Key person on a CDMRP application. These instructions serve as the CDMRP's implementation of the Current and Pending (Other) Support Information Common Form. A complete list of terms and definitions is available in the NSPM-33 Implementation Guidance.

A separate submission must be provided for each proposal and active project, as well as in-kind contributions using the instructions and format specified below.

Consulting activities must be disclosed under the Proposals/Active Projects section of the form when any of the following scenarios apply:

o The consulting activity will require the Senior/Key person to perform research as part of the consulting activity

Consistent with NSPM-33, individuals are required to disclose contracts associated with participation in programs sponsored by foreign governments, instrumentalities, or entities, including foreign government-sponsored talent recruitment programs. Further, if individuals receive direct or indirect support that is funded by a foreign government-sponsored talent recruitment program, even where the support is provided through an intermediary and does not require membership in the foreign government-sponsored talent recruitment program, that support must be disclosed. Individuals must also report other foreign government sponsored or affiliated activities. In accordance with 42 USC 19232, the Malign Foreign Talent Recruitment Program Prohibition Statute, individuals are prohibited from being a party in a malign foreign talent recruitment program.

The table entitled NSPM-33 Implementation Guidance Pre- and Post-award Disclosures Relating to the Biographical Sketch and Current and Pending (Other) Support provides helpful reference information regarding pre-award and post-award disclosures. The table includes the types of activities to be reported, where such activities must be reported in the application, as well as when updates are required in the application and award lifecycle. A final column identifies activities that are not required to be reported.

(1) Identifying Information

(i) Name: Enter the name of the Senior/Key person (Last name, First name, Middle name, including any applicable suffix).

(iii) Position Title: Enter the current position title of the Senior/Key person.

(2) Organization and Location

(i) Name: Enter the name of the primary organization of the Senior/Key person.

(ii) Location: Enter the City, State/Province, and Country where the primary organization is located. If the State/Province is not applicable, enter N/A.

(3) Proposals/Active Projects

In this section, disclose ALL proposals and active projects in accordance with the definitions for current and pending (other) support.

(i) Title: Enter the title of each project/active proposal being reported.

(ii) Status of Support: Select the appropriate status type as defined below:

(iii) Proposal/Active Award Number (if available): Enter the applicable proposal/active award number for each proposal and/or award, if available.

(vi) Proposal/Active Project Start Date: Indicate the start date (MM/YYYY) of the project, as proposed/awarded.

(vii) Proposal/Active Project End Date: Indicate the end date (MM/YYYY) of the project, as proposed/awarded.

(x) Overall Objectives: Provide a brief statement of the overall objectives of the proposal/active project. This field is limited to 1500 characters.

(4) In-Kind Contributions

(i) Status of Support: Select the appropriate status type as defined below:

Current � all in-kind contributions obligated from whatever source irrespective of whether such support is provided through the proposing organization or is provided directly to the individual.

(ii) Receipt (or Anticipated Receipt) Date of In-Kind Contribution: Enter the receipt date (or anticipated receipt date) of the in-kind contribution.

(iii) Source of Support: Identify the entity (entities) that is providing the in-kind contribution. Include, for example, Federal, State, Tribal, territorial, local, foreign,

public or private foundations, non-profit organizations, industrial or other commercial organizations, or internal funds allocated toward specific projects.

(iv) Summary of In-Kind Contribution(s): Enter a summary of the in-kind contribution not intended for use on the proposal/active project.

(vii) Overall Objectives: Provide a brief statement of the overall objectives of the in-kind contribution(s). This field is limited to 1500 characters.

(5) Certification

Each Senior/Key person is required to complete the following certifications regarding the information provided in their Current and Pending (Other) Support:

I certify that the information provided is current, accurate and complete. This includes, but is not limited to, information related to current, pending, and other support (both foreign and domestic) as defined in 42 U.S.C. �6605. I also certify that, at the time of submission, I am not a party in a malign foreign talent recruitment program.

Misrepresentations and/or omissions may be subject to prosecution and liability pursuant to, but not limited to, 18 U.S.C. ��287, 1001, 1031 and 31 U.S.C. ��3729-3733 and 3802.

Signature and Date: To be acceptable, the date of the signature must be within the past 12 months from when the document is submitted.

(c) Budget Form

The total proposed research project cost, with a breakdown of all cost categories for each year of the project, must be submitted. Complete a separate Suggested Intragovernmental/Intramural Budget Form that covers all years of the period of performance for each research site involved in the project (including subaward sites) and upload to Tab 3 � Full Application Files as a single

document titled �IGBudget.pdf�. The Suggested Intragovernmental/Intramural Budget Form is available for download on the eBRAP Funding Opportunities and Forms page. For limits on funding amounts, types of costs, and period of performance, refer to the program announcement. A budget justification for the entire period of performance that includes a Federal Financial Plan must be appended to the Suggested Intragovernmental/Intramural Budget Form. The budget and budget justification should include sufficient detail for the government to determine whether the proposed costs are allowable, allocable, and reasonable for the proposed research. The government reserves the right to request a revised budget and budget justification and/or additional information.

If the budget fails eBRAP validation, the PI will receive an error message and will be required to correct the budget within the existing application prior to the full application submission deadline. Any additional modifications to the budget must also be completed prior to the full application submission deadline.

Budget Regulations and Restrictions:

� Administrative and Cost Principles: Recipients will be required to comply with the following, as applicable:

○ 2 CFR 200, Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards, as implemented by Chapter XI of Title 2 CFR.

○ FAR Part 31, Contract Cost Principles and Procedures.

� Cost of Preparing Applications: The cost of preparing applications in response to a program announcement is not considered an allowable direct charge to any resultant award. However, the cost of preparing applications may be an allowable cost that can be included in the indirect/F&A cost as specified in the organization�s applicable cost principles.

� Currency: All costs must be entered in U.S. dollars.

Intragovernmental/Intramural Budget Form Instructions:

Begin by entering the organization name, PI name, and eBRAP Log number in the fields at the top.

Name: Beginning with the PI, list all key personnel who will be involved in the project during the initial budget period, whether or not salaries are requested. Include all collaborating investigators, research associates, individuals in training, mentor (if applicable), and support staff who will contribute significantly to the proposed research project.

DOD Civilian and Military Personnel: Personnel involved in the project should be listed in this section; however, this award is not intended to provide salary support for any federal employee. Generally, RDT&E funds may only be requested to support civilian salaries for those individuals who are in reimbursable positions. These circumstances will be discussed during award negotiations and will require substantial justification in the Budget Justification section.

Role/Key Personnel: Identify the role of each participant listed. Describe their specific functions in the proposed research in the budget justification.
Title/Position/Rank: Identify the title, position, or rank for each individual.
Annual Base Salary: Enter the annual organizational base salary (based on a full-time appointment) for each individual requesting salary reimbursement listed for the project. If no reimbursement is requested, leave the Annual Base Salary section blank.
Effort on Project: List the percentage of each appointment to be spent on this project for all staff members including unpaid personnel.
Salary Requested: Enter the salary for each position for which funds are requested. This is calculated automatically from the data provided.
Fringe Benefits: Enter the fringe benefits requested for each individual in accordance with organizational guidelines.
Totals: Calculated automatically from the salaries and fringe benefits data provided. Ensure the totals are correctly auto-calculated.
Consultant Costs: List the total costs for any consultant fees/services.
Equipment: Provide the cost of proposed equipment. Equipment is tangible personal property (including information technology systems) having a useful life of more than one year and a per-unit acquisition cost that equals or exceeds the lesser of: (1) $5,000; or (2) the recipient�s or the subrecipient�s capitalization threshold for financial statement purposes. Applicant organizations are encouraged to provide all equipment necessary to conduct the proposed research project.
Materials and Supplies: Materials and supplies are all tangible property, including a computing device, acquired under an award that does not meet the definition of equipment.
Military and Federal Civilian Travel Costs: Applicants are responsible for budgeting all costs associated with travel, including airfare, hotel, etc., associated with the trip. Anticipated travel costs should be built into the budget at current or projected DOD per diem rates. Note, military and federal civilian travel costs, unless funded via a project order, cannot not be subjected to fees/indirect costs.
Contractor Travel Costs: For contractor personnel, indicate all travel costs associated with travel, including airfare, hotel, etc., associated with the trip. Anticipated travel costs should be built into the budget at current or projected DOD per diem rates.

Other Direct Costs: Itemize other anticipated direct costs such as research-related subject cost, publication and report costs, equipment rental (provide hours and rates), communication costs, and organizationally provided services. Estimate the costs of publishing and reporting research results, including direct charges for clerical services, illustrations, reprints and distribution. Organizationally provided services should be supported by the organization�s current cost/rate schedule. These items should be described in detail and clearly justified.
Sub-Award/Contract Costs (Partnership/Collaboration Costs): Should an intramural organization propose collaboration with an extramural entity for part of the research effort, the intramural organization will receive all funds and is responsible for executing all necessary contractual or assistance funding awards to collaborating partners through the agency�s procedures. The nature of the partnership/collaboration should be described in the Sub-Award/Contract Budget Justification section.

All direct and indirect costs of any subaward/contract must be included in the direct costs of the primary award.

Total Direct Costs: Calculated automatically from the data provided for the initial budget period and for the entire proposed period of support.

The primary award (including the direct and indirect costs of any subawardees/subcontractors, if applicable) should not exceed the cost limit stated in the program announcement.

Total Indirect Costs: If funds for indirect costs are requested, sufficient justification must be provided in the Justification section. The government reserves the right to disallow any indirect costs not sufficiently justified. No budget will be approved by the government using an indirect rate exceeding the organization�s negotiated rate.
Total Direct and Indirect Costs: This section is calculated automatically from the data provided.
Required Information (last page of the form):

○ Indicate the name and contact information for the Resource Management, Business Official, and any parties who should be included on budgetary matters.

○ Indicate the last date the institution can accept current fiscal year funds.

○ The authorized organization representative must: (1) attest that the organization has a system in place to accept funds; (2) acknowledge that receipt of funds may occur within the last six months of the current fiscal year; and (3) sign the document.

Budget Justification Instructions:

Provide a clear budget justification for the entire period of performance for each item in the budget. Append the Budget Justification to the Suggested Intragovernmental/Intramural Budget Form and upload as a single document. It is recommended that the headings of the cost categories in the budget justification match the cost categories in the Suggested Intragovernmental/Intramural Budget Form. Itemize direct

costs for all years of the award. Organizations must provide sufficient detail and justification so the government can determine that the proposed costs are allowable, allocable, and reasonable for the proposed research effort. Applicants performing research outside of the United States should also include the cost in local currency, the rate used for converting to U.S. dollars, and justification/basis for the conversion rate used. Foreign currency exchange rates for applicants performing research outside of the United States will be determined at the time of application submission.

Travel: If travel costs are requested to attend scientific/technical meetings, include the meeting name, purpose, location and date, if known. International travel may be requested but must be justified with additional documentation and is subject to approval by the Program Office. The justification should clearly confirm that the requested travel costs meet any travel requirements and/or restrictions stated in the program announcement.

Service Costs and User Fees: List proposed equipment or facility rental/user fees, including data processing fees. Include information regarding estimated hours/units required for the proposed research project and the provider�s service rates.

Other Expenses: Describe and justify any other anticipated direct costs.

Indirect Costs: Provide details of the direct cost base (modified total direct costs, salary and wage, or other). Identify any costs that have been excluded from the base (in accordance with the approved rate agreement). Also indicate if the rate(s) is an on-site or off-site rate(s). If more than one rate is applicable, provide a breakdown of the calculation.

Federal Financial Plan: The CDMRP�s funding is directed by Congress on a yearly basis for each program and is obligated up front for each award as there is no guarantee of future program appropriations. Funds are available for obligation for two years from the beginning of the fiscal year of appropriation. For applications involving an intragovernmental or intramural DOD organization, include a federal financial plan in the budget justification. The plan must address how any funds transferred to the intragovernmental or intramural DOD organization will be obligated before their expiration for obligation, and how funds will be available to cover research costs over the entire award period. The plan must include the funding mechanism(s) that will be used to carry over funds between fiscal years, if applicable. The CDMRP encourages intramural DOD applicants to plan for the transfer of funding via Project Orders, where applicable. Unless otherwise stated in the funding opportunity, the CDMRP does not intend to use funds from future fiscal year(s), if appropriated, to support the award.

Foreign Collaboration Justification: Applications that propose consultant, subaward, consortium, or contractual arrangements with foreign organizations or collaborators employed by foreign organizations/governments are required to demonstrate how one or more of the following conditions have been met:

� The foreign organization or individual(s) employed by foreign organizations/governments contributes unique expertise, organizational capability, facilities, data resources, and/or access to a geographic location or population not generally available to investigators based in the United States (or which would require significant effort or time to duplicate) or would potentially significantly advance the health sciences in the United States.

� The foreign organization, individual(s) employed by foreign organizations/governments, or project offers significant unique health research opportunities to advance U.S. Military medicine and benefit Service Members, Veterans and their Families.

(d) Project/Performance Site Location(s) Form

Upload the Project/Performance Site Location(s) Form as �Performance.pdf� to Tab 3 � Full Application Files.

Upon application submission, the organizational RM/Comptroller/Task Area Manager or equivalent Business Official will receive an email instructing them to log into eBRAP to review and approve the full application submission. eBRAP will validate full application files against the specific program announcement requirements, and discrepancies will be noted in the Full Application Files tab. However, eBRAP does not confirm the accuracy of file content. It is the applicant�s responsibility to review all application components and ensure proper ordering as specified in the program announcement. Verification of application content is strongly recommended but not required. Modifications to application components may only be made after the Business Official has set the status to �Return to PI� for the PI to make changes, or to �Draft� for the Business Official to make changes.

The Project Narrative and the Research & Related Budget Form cannot be changed after the application submission deadline.

Other application components, including subaward budget(s) and subaward budget justification(s), may be changed until the end of the application verification period. The full application cannot be modified once the application verification period ends. The RM/Comptroller/Task Area Manager or equivalent Business Official should log into eBRAP to review and to approve the application package prior to the application verification deadline.

A&R	Alteration and Renovation
ACURO	Animal Care and Use Review Office
ADP	Automated Data Processing
AL	Assistance Listing (formerly, Catalog of Federal Domestic Assistance [CFDA])
AOR	Authorized Organizational Representative
AVI	Audio Video Interleave
BAA	Broad Agency Announcement
BMP	Bitmap File Format for Digital Images
CAGE	Commercial and Government Entity
CDC	U.S. Centers for Disease Control and Prevention
CDMRP	Congressionally Directed Medical Research Programs
CFR	Code of Federal Regulations
CRADA	Cooperative Research and Development Agreement
CSI	Congressional Special Interest
DHA	Defense Health Agency
DHHS	U.S. Department of Health and Human Services
DOD	U.S. Department of Defense
DoDI	Department of Defense Instruction
DoDGARs	Department of Defense Grant and Agreement Regulations
DTIC	Defense Technical Information Center
DURC	Dual Use Research of Concern
E-Biz	Electronic Business
eBRAP	electronic Biomedical Research Application Portal
EC	Ethics Committee
EIN	Employer Identification Number
F&A	Facilities and Administrative
FAD	Funding Authorization Document
FAR	Federal Acquisition Regulation
FDA	U.S. Food and Drug Administration
FOA	Funding Opportunity Announcement
FOIA	Freedom of Information Act
FWA	Federalwide Assurance
FY	Fiscal Year
G&A	General and Administrative
GAI	General Application Instructions
GSA	U.S. General Services Administration
HIPAA	Health Insurance Portability and Accountability Act
IACUC	Institutional Animal Care and Use Committee
IRB	Institutional Review Board
IRP	Inquiry Review Process
JPEG	Joint Photographic Experts Group
LSGD	Large-Scale Genomic Data
MB	Megabyte
MIPR	Military Interdepartmental Purchase Request
MPEG	Moving Picture Experts Group
NCAGE	North Atlantic Treaty Organization Commercial and Government Entity
NIH	National Institutes of Health
NSF	U.S. National Science Foundation
NSPM-33	National Security Presidential Memorandum-33
OHARO	Office of Human and Animal Research Oversight (previously Office of Research Protections)
OHRO	Office of Human Research Oversight (previously Human Research Protection Office)
ORCID	Open Researcher and Contributor ID
PD	Project Director
PDF	Portable Document Format
PI	Principal Investigator
POC	Point of Contact
RDT&E	Research, Development, Test and Evaluation
RM	Resource Manager
R&R	Research & Related
SAM	System for Award Management
SciENcv	Science Experts Network Curriculum Vitae
SF	Standard Form
SFLLL	Disclosure of Lobbying Activities Standard Form LLL on Grants.gov
SF424 (R&R)	Application for Federal Assistance Standard Form 424 (Research & Related) on Grants.gov
SOW	Statement of Work
STEM	Science, Technology, Engineering and/or Mathematics
TIFF	Tagged Image File Format
TIN	Tax Identification Number
UEI	Unique Entity Identifier
URL	Uniform Resource Locator
USAMRAA	U.S. Army Medical Research Acquisition Activity
USAMRDC	U.S. Army Medical Research and Development Command
USC	United States Code
VA	U.S. Department of Veterans Affairs
WAV	Waveform Audio